Cargando…

Chi hotspot control of RecBCD helicase-nuclease by long-range intramolecular signaling

Repair of broken DNA by homologous recombination requires coordinated enzymatic reactions to prepare it for interaction with intact DNA. The multiple activities of enterobacterial RecBCD helicase-nuclease are coordinated by Chi recombination hotspots (5′ GCTGGTGG 3′) recognized during DNA unwinding....

Descripción completa

Detalles Bibliográficos
Autores principales:	Amundsen, Susan K., Taylor, Andrew F., Smith, Gerald R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644769/ https://www.ncbi.nlm.nih.gov/pubmed/33154402 http://dx.doi.org/10.1038/s41598-020-73078-0

Ejemplares similares

The RecB helicase-nuclease tether mediates Chi hotspot control of RecBCD enzyme
por: Amundsen, Susan K, et al.
Publicado: (2019)

Small-molecule sensitization of RecBCD helicase–nuclease to a Chi hotspot-activated state
por: Karabulut, Ahmet C, et al.
Publicado: (2020)

Mechanism for nuclease regulation in RecBCD
por: Wilkinson, Martin, et al.
Publicado: (2016)

chi sequences switch the RecBCD helicase–nuclease complex from degradative to replicative modes during the completion of DNA replication
por: Hamilton, Nicklas A., et al.
Publicado: (2023)

Structural features of Chi recognition in AddAB with implications for RecBCD
por: Wilkinson, Martin, et al.
Publicado: (2014)

The positioning of Chi sites allows the RecBCD pathway to suppress some genomic rearrangements
por: Li, Chastity, et al.
Publicado: (2019)

A conformational switch in response to Chi converts RecBCD from phage destruction to DNA repair
por: Cheng, Kaiying, et al.
Publicado: (2020)

Synergy between RecBCD subunits is essential for efficient DNA unwinding
por: Zananiri, Rani, et al.
Publicado: (2019)

Auxiliary ATP binding sites support DNA unwinding by RecBCD
por: Zananiri, Rani, et al.
Publicado: (2022)

CRISPR–Cas adaptation in Escherichia coli requires RecBCD helicase but not nuclease activity, is independent of homologous recombination, and is antagonized by 5′ ssDNA exonucleases
por: Radovčić, Marin, et al.
Publicado: (2018)

Biochemical characterization of RecBCD enzyme from an Antarctic Pseudomonas species and identification of its cognate Chi (χ) sequence
por: Pavankumar, Theetha L., et al.
Publicado: (2018)

DNA Unwinding Heterogeneity by RecBCD Results from Static Molecules Able to Equilibrate
por: Liu, Bian, et al.
Publicado: (2013)

Structural basis for the inhibition of RecBCD by Gam and its synergistic antibacterial effect with quinolones
por: Wilkinson, Martin, et al.
Publicado: (2016)

Sequence-dependent nanometer-scale conformational dynamics of individual RecBCD–DNA complexes
por: Carter, Ashley R., et al.
Publicado: (2016)

A non-catalytic role of RecBCD in homology directed gap repair and translesion synthesis
por: Laureti, Luisa, et al.
Publicado: (2017)

Direct observation of end resection by RecBCD during double-stranded DNA break repair in vivo
por: Wiktor, Jakub, et al.
Publicado: (2018)

Deficiency of RecA-dependent RecFOR and RecBCD pathways causes increased instability of the (GAA·TTC)(n) sequence when GAA is the lagging strand template
por: Pollard, Laura M., et al.
Publicado: (2007)

RecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplification
por: White, Martin A, et al.
Publicado: (2018)

Single-Stranded DNA-Binding Protein and Exogenous RecBCD Inhibitors Enhance Phage-Derived Homologous Recombination in Pseudomonas
por: Yin, Jia, et al.
Publicado: (2019)

Role for DNA double strand end-resection activity of RecBCD in control of aberrant chromosomal replication initiation in Escherichia coli
por: Goswami, Sayantan, et al.
Publicado: (2022)

Structures of RecBCD in complex with phage-encoded inhibitor proteins reveal distinctive strategies for evasion of a bacterial immunity hub
por: Wilkinson, Martin, et al.
Publicado: (2022)

Division-induced DNA double strand breaks in the chromosome terminus region of Escherichia coli lacking RecBCD DNA repair enzyme
por: Sinha, Anurag Kumar, et al.
Publicado: (2017)

All Three Subunits of RecBCD Enzyme Are Essential for DNA Repair and Low-Temperature Growth in the Antarctic Pseudomonas syringae Lz4W
por: Pavankumar, Theetha L., et al.
Publicado: (2010)

Unexpected DNA context-dependence identifies a new determinant of Chi recombination hotspots
por: Taylor, Andrew F., et al.
Publicado: (2016)

Insights into Chi recognition from the structure of an AddAB-type helicase–nuclease complex
por: Saikrishnan, Kayarat, et al.
Publicado: (2012)

Structural basis for translocation by AddAB helicase/nuclease and its arrest at Chi sites
por: Krajewski, Wojciech W., et al.
Publicado: (2014)

The RecD2 helicase balances RecA activities
por: Ramos, Cristina, et al.
Publicado: (2022)

Recombination hotspots attenuate the coupled ATPase and translocase activities of an AddAB-type helicase–nuclease
por: Gilhooly, Neville S., et al.
Publicado: (2014)

Characterization of the Neisseria meningitidis Helicase RecG
por: Beyene, Getachew Tesfaye, et al.
Publicado: (2016)

RecQ Helicase Somatic Alterations in Cancer
por: Thakkar, Megha K., et al.
Publicado: (2022)

Chi hotspots trigger a conformational change in the helicase-like domain of AddAB to activate homologous recombination
por: Gilhooly, Neville S., et al.
Publicado: (2016)

RecQ helicases: lessons from model organisms
por: Cobb, Jennifer A., et al.
Publicado: (2006)

RecQ helicases in DNA repair and cancer targets
por: Newman, Joseph A., et al.
Publicado: (2020)

Transcodeur BCD - binaire pur
por: Tiger, F
Publicado: (1970)

Function of the N-terminal segment of the RecA-dependent nuclease Ref
por: Gruber, Angela J., et al.
Publicado: (2015)

DNA helicase and helicase–nuclease enzymes with a conserved iron–sulfur cluster
por: Wu, Yuliang, et al.
Publicado: (2012)

Insights into the RecQ helicase mechanism revealed by the structure of the helicase domain of human RECQL5
por: Newman, Joseph A., et al.
Publicado: (2017)

Human premature aging, DNA repair and RecQ helicases
por: Brosh, Robert M., et al.
Publicado: (2007)

ATPase Cycle and DNA Unwinding Kinetics of RecG Helicase
por: Toseland, Christopher P., et al.
Publicado: (2012)

Structural mechanisms of human RecQ helicases WRN and BLM
por: Kitano, Ken
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lr468fla8vv2orv95da67bdgiq