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SOCS, Intrinsic Virulence Factors, and Treatment of COVID-19

The suppressor of cytokine signaling (SOCS) family of intracellular checkpoint inhibitors has received little recognition compared to other checkpoint inhibitors. Two members of this family, SOCS1 and SOCS3, are indispensable, since SOCS1 knockout in mice results in neonatal death due to interferon...

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Detalles Bibliográficos
Autores principales: Johnson, Howard M., Lewin, Alfred S., Ahmed, Chulbul M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644869/
https://www.ncbi.nlm.nih.gov/pubmed/33193390
http://dx.doi.org/10.3389/fimmu.2020.582102