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The Creatine Transporter Unfolded: A Knotty Premise in the Cerebral Creatine Deficiency Syndrome

Creatine provides cells with high-energy phosphates for the rapid reconstitution of hydrolyzed adenosine triphosphate. The eponymous creatine transporter (CRT1/SLC6A8) belongs to a family of solute carrier 6 (SLC6) proteins. The key role of CRT1 is to translocate creatine across tissue barriers and...

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Detalles Bibliográficos
Autores principales: Farr, Clemens V., El-Kasaby, Ali, Freissmuth, Michael, Sucic, Sonja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644880/
https://www.ncbi.nlm.nih.gov/pubmed/33192443
http://dx.doi.org/10.3389/fnsyn.2020.588954