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Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization Approaches

BACKGROUND: Telomere length is an important indicator of tumor progression and survival for cancer patients. Previous work investigated the associations between genetically predicted telomere length and cancers; however, the types of cancers investigated in those studies were relatively limited or t...

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Detalles Bibliográficos
Autores principales: Gao, Yixin, Wei, Yongyue, Zhou, Xiang, Huang, Shuiping, Zhao, Huashuo, Zeng, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644901/
https://www.ncbi.nlm.nih.gov/pubmed/33193711
http://dx.doi.org/10.3389/fgene.2020.583106