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Deficiency of LMP10 Attenuates Diet-Induced Atherosclerosis by Inhibiting Macrophage Polarization and Inflammation in Apolipoprotein E Deficient Mice

Macrophage polarization and inflammation are key factors for the onset and progression of atherosclerosis. The immunoproteasome complex consists of three inducible catalytic subunits (LMP2, LMP10, and LMP7) that play a critical role in the regulation of these risk factors. We recently demonstrated t...

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Detalles Bibliográficos
Autores principales: Liao, Jiawei, An, Xiangbo, Yang, Xiaolei, Lin, Qiu-Yue, Liu, Shuang, Xie, Yunpeng, Bai, Jie, Xia, Yun-Long, Li, Hui-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7644912/
https://www.ncbi.nlm.nih.gov/pubmed/33195259
http://dx.doi.org/10.3389/fcell.2020.592048