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Combined Optogenetic Approaches Reveal Quantitative Dynamics of Endogenous Noradrenergic Transmission in the Brain

Little is known about the real-time cellular dynamics triggered by endogenous catecholamine release despite their importance in brain functions. To address this issue, we expressed channelrhodopsin in locus coeruleus neurons and protein kinase-A activity biosensors in cortical pyramidal neurons and...

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Detalles Bibliográficos
Autores principales: Nomura, Shinobu, Tricoire, Ludovic, Cohen, Ivan, Kuhn, Bernd, Lambolez, Bertrand, Hepp, Régine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645030/
https://www.ncbi.nlm.nih.gov/pubmed/33196030
http://dx.doi.org/10.1016/j.isci.2020.101710