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Combined Optogenetic Approaches Reveal Quantitative Dynamics of Endogenous Noradrenergic Transmission in the Brain
Little is known about the real-time cellular dynamics triggered by endogenous catecholamine release despite their importance in brain functions. To address this issue, we expressed channelrhodopsin in locus coeruleus neurons and protein kinase-A activity biosensors in cortical pyramidal neurons and...
Autores principales: | Nomura, Shinobu, Tricoire, Ludovic, Cohen, Ivan, Kuhn, Bernd, Lambolez, Bertrand, Hepp, Régine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645030/ https://www.ncbi.nlm.nih.gov/pubmed/33196030 http://dx.doi.org/10.1016/j.isci.2020.101710 |
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