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Methylation-Mediated Silencing of MicroRNA-497 Promotes Breast Cancer Progression Through Up-Regulation of Mucin1

BACKGROUND: Potential anti-tumor effects of microRNA-497 (miR-497) have been highlighted in various malignancies including breast cancer. However, little is known about the function of miR-497 and its putative target mucin1 (MUC1) in breast cancer. The present study explored how miR-497 regulates br...

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Detalles Bibliográficos
Autores principales: Tao, Shuang, Li, Hong, Ma, Xiuzhen, Lian, Bin, He, Jiale, Gao, Yali, Li, Jinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645108/
https://www.ncbi.nlm.nih.gov/pubmed/33194611
http://dx.doi.org/10.3389/fonc.2020.552099