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Inflammatory Cytokines Alter Mesenchymal Stem Cell Mechanosensing and Adhesion on Stiffened Infarct Heart Tissue After Myocardial Infarction

Mesenchymal stem cell (MSC) transplantation has demonstrated its potential in repairing infarct heart tissue and recovering heart function after myocardial infarction (MI). However, its therapeutic effect is still limited due to poor MSC engraftment at the injury site whose tissue stiffness and loca...

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Detalles Bibliográficos
Autores principales: Zhu, Dan, Wu, Peng, Xiao, Changchen, Hu, Wei, Zhang, Tongtong, Hu, Xinyang, Chen, Wei, Wang, Jian’an
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645114/
https://www.ncbi.nlm.nih.gov/pubmed/33195229
http://dx.doi.org/10.3389/fcell.2020.583700