Malformation of Tear Ducts Underlies the Epiphora and Precocious Eyelid Opening in Prickle 1 Mutant Mice: Genetic Implications for Tear Duct Genesis

PURPOSE: Obstruction of the tear drainage causes a range of ocular surface disorders. Hitherto, the genetics of tear duct development and obstruction has been scarcely explored, and related animal models are lacking. This study aims to study the potential role of the Wnt/PCP pathway mediated by Pric...

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Detalles Bibliográficos
Autores principales: Ru, Jiali, Guo, Dianlei, Fan, Jiaying, Zhang, Jiao, Ju, Rong, Ouyang, Hong, Wei, Lai, Liu, Yizhi, Liu, Chunqiao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2020
Materias:
Anatomy and Pathology/Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645213/
https://www.ncbi.nlm.nih.gov/pubmed/33141892
http://dx.doi.org/10.1167/iovs.61.13.6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645213/
https://www.ncbi.nlm.nih.gov/pubmed/33141892
http://dx.doi.org/10.1167/iovs.61.13.6

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