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A 3D Cell Culture Organ-on-a-Chip Platform With a Breathable Hemoglobin Analogue Augments and Extends Primary Human Hepatocyte Functions in vitro

Remarkable advances in three-dimensional (3D) cell cultures and organ-on-a-chip technologies have opened the door to recapitulate complex aspects of human physiology, pathology, and drug responses in vitro. The challenges regarding oxygen delivery, throughput, assay multiplexing, and experimental co...

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Detalles Bibliográficos
Autores principales: Shoemaker, James T., Zhang, Wanrui, Atlas, Selin I., Bryan, Richard A., Inman, S. Walker, Vukasinovic, Jelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645268/
https://www.ncbi.nlm.nih.gov/pubmed/33195413
http://dx.doi.org/10.3389/fmolb.2020.568777