DNA methylation profiling of CD04(+)/CD08(+) T cells reveals pathogenic mechanisms in increasing hyperglycemia: PIRAMIDE pilot study

BACKGROUND: DNA methylation can play a pathogenic role in the early stages of hyperglycemia linking homeostasis imbalance and vascular damage. MATERIAL AND METHODS: We investigated DNA methylome by RRBS in CD04(+) and CD08(+) T cells from healthy subjects (HS) to pre-diabetics (Pre-Diab) and type 2...

Descripción completa

Detalles Bibliográficos
Autores principales: Benincasa, Giuditta, Franzese, Monica, Schiano, Concetta, Marfella, Raffaele, Miceli, Marco, Infante, Teresa, Sardu, Celestino, Zanfardino, Mario, Affinito, Ornella, Mansueto, Gelsomina, Sommese, Linda, Nicoletti, Giovanni Francesco, Salvatore, Marco, Paolisso, Giuseppe, Napoli, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Cross-sectional Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645316/
https://www.ncbi.nlm.nih.gov/pubmed/33194177
http://dx.doi.org/10.1016/j.amsu.2020.10.016

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645316/
https://www.ncbi.nlm.nih.gov/pubmed/33194177
http://dx.doi.org/10.1016/j.amsu.2020.10.016

Ejemplares similares