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Knockdown of CK2α reduces P-cresol-induced fibrosis in human renal proximal tubule epithelial cells via the downregulation of profilin-1

Renal fibrosis is one of the main causes of chronic kidney disease. Many studies have focused on fibroblasts and myofibroblasts involved in renal fibrogenesis. Recently, several studies have reported that renal proximal tubule epithelial cells are possible initiators of renal fibrosis. However, the...

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Detalles Bibliográficos
Autores principales: Yoon, Yeo Min, Go, Gyeongyun, Yun, Chul Won, Lim, Ji Ho, Lee, Sang Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645352/
https://www.ncbi.nlm.nih.gov/pubmed/33162813
http://dx.doi.org/10.7150/ijms.48429