LSD1 inhibition induces differentiation and cell death in Merkel cell carcinoma

Merkel cell carcinoma (MCC) is a highly aggressive, neuroendocrine skin cancer that lacks actionable mutations, which could be utilized for targeted therapies. Epigenetic regulators governing cell identity may represent unexplored therapeutic entry points. Here, we targeted epigenetic regulators in...

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Detalles Bibliográficos
Autores principales: Leiendecker, Lukas, Jung, Pauline S, Krecioch, Izabela, Neumann, Tobias, Schleiffer, Alexander, Mechtler, Karl, Wiesner, Thomas, Obenauf, Anna C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645387/
https://www.ncbi.nlm.nih.gov/pubmed/33026191
http://dx.doi.org/10.15252/emmm.202012525

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645387/
https://www.ncbi.nlm.nih.gov/pubmed/33026191
http://dx.doi.org/10.15252/emmm.202012525

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