Evidence for a non-stochastic two-field hypothesis for persistent skin cancer risk

With recurring carcinogen exposures, individual tumors develop in a field of genetic mutations through a stepwise process of clonal expansion and evolution. Once established, this “cancer field” persists in the absence of continued carcinogen exposures, resulting in a sustained risk for cancer devel...

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Detalles Bibliográficos
Autores principales: Konger, Raymond L., Ren, Lu, Sahu, Ravi P., Derr-Yellin, Ethel, Kim, Young L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645611/
https://www.ncbi.nlm.nih.gov/pubmed/33154396
http://dx.doi.org/10.1038/s41598-020-75864-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645611/
https://www.ncbi.nlm.nih.gov/pubmed/33154396
http://dx.doi.org/10.1038/s41598-020-75864-2

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