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Azure B as a novel cyanide antidote: Preclinical in-vivo studies

We have determined the effects of azure B (AzB), the main demethylated metabolite of methylene blue (MB), on a model of lethal cyanide intoxication. Our rationale was the following: AzB 1- possesses redox properties very similar to those of MB, which is a potent cyanide antidote, 2- may present a hi...

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Detalles Bibliográficos
Autores principales: Haouzi, Philippe, McCann, Marissa, Tubbs, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645636/
https://www.ncbi.nlm.nih.gov/pubmed/33194557
http://dx.doi.org/10.1016/j.toxrep.2020.10.015