Female sex mitigates motor and behavioural phenotypes in TDP-43(Q331K) knock-in mice

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are overlapping neurodegenerative disorders. ALS is more commonly seen in men than women and the same may be the case for FTD. Preclinical models demonstrating sex-specific vulnerability may help to understand female resistance to...

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Detalles Bibliográficos
Autores principales: Watkins, Jodie, Ghosh, Anshua, Keerie, Amy F. A., Alix, James J. P., Mead, Richard J., Sreedharan, Jemeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645778/
https://www.ncbi.nlm.nih.gov/pubmed/33154447
http://dx.doi.org/10.1038/s41598-020-76070-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645778/
https://www.ncbi.nlm.nih.gov/pubmed/33154447
http://dx.doi.org/10.1038/s41598-020-76070-w

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