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Role of the EF-hand and coiled-coil domains of human Rab44 in localisation and organelle formation

Rab44 is a large Rab GTPase that contains an amino-terminal EF-hand domain, a coiled-coil domain, and a carboxyl-terminal Rab GTPase domain. However, the roles of the EF-hand and coiled-coil domains remain unclear. Here, we constructed various deletion and point mutants of human Rab44. When overexpr...

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Detalles Bibliográficos
Autores principales: Ogawa, Kohei, Kadowaki, Tomoko, Tokuhisa, Mitsuko, Yamaguchi, Yu, Umeda, Masahiro, Tsukuba, Takayuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645795/
https://www.ncbi.nlm.nih.gov/pubmed/33154405
http://dx.doi.org/10.1038/s41598-020-75897-7