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N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease
The genome of coronaviruses, including SARS‐CoV‐2, encodes for two proteases, a papain like (PL(pro)) protease and the so‐called main protease (M(pro)), a chymotrypsin‐like cysteine protease, also named 3CL(pro) or non‐structural protein 5 (nsp5). M(pro) is activated by autoproteolysis and is the ma...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645863/ https://www.ncbi.nlm.nih.gov/pubmed/33111431 http://dx.doi.org/10.1002/pmic.202000246 |