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N‐Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS‐CoV‐2 Main Protease

The genome of coronaviruses, including SARS‐CoV‐2, encodes for two proteases, a papain like (PL(pro)) protease and the so‐called main protease (M(pro)), a chymotrypsin‐like cysteine protease, also named 3CL(pro) or non‐structural protein 5 (nsp5). M(pro) is activated by autoproteolysis and is the ma...

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Detalles Bibliográficos
Autores principales:	Koudelka, Tomas, Boger, Juliane, Henkel, Alessandra, Schönherr, Robert, Krantz, Stefanie, Fuchs, Sabine, Rodríguez, Estefanía, Redecke, Lars, Tholey, Andreas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Dataset Briefs
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7645863/ https://www.ncbi.nlm.nih.gov/pubmed/33111431 http://dx.doi.org/10.1002/pmic.202000246

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