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A Hydrophobic‐Interaction‐Based Mechanism Triggers Docking between the SARS‐CoV‐2 Spike and Angiotensin‐Converting Enzyme 2

A recent experimental study found that the binding affinity between the cellular receptor human angiotensin‐converting enzyme 2 (ACE2) and receptor‐binding domain (RBD) in the spike (S) protein of novel severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) is more than tenfold higher than tha...

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Detalles Bibliográficos
Autores principales: Li, Jiacheng, Ma, Xiaoliang, Guo, Shuai, Hou, Chengyu, Shi, Liping, Zhang, Hongchi, Zheng, Bing, Liao, Chenchen, Yang, Lin, Ye, Lin, He, Xiaodong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646041/
https://www.ncbi.nlm.nih.gov/pubmed/33173592
http://dx.doi.org/10.1002/gch2.202000067