Cargando…

Forced exercise activates the NrF2 pathway in the striatum and ameliorates motor and behavioral manifestations of Parkinson's disease in rotenone-treated rats

BACKGROUND: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons leading to dopamine depletion and problems of movement, emotions, and cognition. While the pathogenesis of PD is not clear, damage of dopaminergic...

Descripción completa

Detalles Bibliográficos
Autores principales: Monir, Dina M., Mahmoud, Motamed E., Ahmed, Omyma G., Rehan, Ibrahim F., Abdelrahman, Amany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646065/
https://www.ncbi.nlm.nih.gov/pubmed/33158454
http://dx.doi.org/10.1186/s12993-020-00171-9