Cargando…

Forced exercise activates the NrF2 pathway in the striatum and ameliorates motor and behavioral manifestations of Parkinson's disease in rotenone-treated rats

BACKGROUND: Parkinson's disease (PD) is a common neurodegenerative disorder characterized by progressive loss of nigrostriatal dopaminergic neurons leading to dopamine depletion and problems of movement, emotions, and cognition. While the pathogenesis of PD is not clear, damage of dopaminergic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Monir, Dina M., Mahmoud, Motamed E., Ahmed, Omyma G., Rehan, Ibrahim F., Abdelrahman, Amany
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646065/ https://www.ncbi.nlm.nih.gov/pubmed/33158454 http://dx.doi.org/10.1186/s12993-020-00171-9

Ejemplares similares

Piracetam and vinpocetine ameliorate rotenone-induced Parkinsonism in rats
por: Zaitone, Sawsan A., et al.
Publicado: (2012)

Rotenone, Paraquat, and Parkinson’s Disease
por: Tanner, Caroline M., et al.
Publicado: (2011)

Attenuated levels of phospholipids in the striatum of rats infused with rotenone causing hemiparkinsonism as detected by simple dye-lipid complex
por: Gopi, Margabandhu, et al.
Publicado: (2017)

Tryptophan in the diet ameliorates motor deficits in a rotenone‐induced rat Parkinson's disease model via activating the aromatic hydrocarbon receptor pathway
por: Wang, Yilin, et al.
Publicado: (2021)

Rotenone ameliorates chronic renal injury caused by acute ischemia/reperfusion
por: Zhang, Wen, et al.
Publicado: (2018)

Monoterpenoid Epoxidiol Ameliorates the Pathological Phenotypes of the Rotenone-Induced Parkinson’s Disease Model by Alleviating Mitochondrial Dysfunction
por: Aleksandrova, Yulia, et al.
Publicado: (2023)

The effect of low dose amphetamine in rotenone-induced toxicity in a mice model of Parkinson’s disease
por: Abdel-Salam, Omar M.E., et al.
Publicado: (2020)

Lesioning of the Striatum Reverses Motor Asymmetry in the 6-Hydroxydopamine Rodent Model of Parkinsonism
por: Friehs, G. M., et al.
Publicado: (1991)

Rosinidin inhibits NF-κB/ Nrf2/caspase-3 expression and restores neurotransmitter levels in rotenone-activated Parkinson's disease
por: Alghamdi, Amira M., et al.
Publicado: (2023)

Motor thalamus supports striatum-driven reinforcement
por: Lalive, Arnaud L, et al.
Publicado: (2018)

Quercetin exhibits potent antioxidant activity, restores motor and non-motor deficits induced by rotenone toxicity
por: Madiha, Syeda, et al.
Publicado: (2021)

Presence of insoluble Tau following rotenone exposure ameliorates basic pathways associated with neurodegeneration
por: Chaves, Rodrigo S., et al.
Publicado: (2016)

The role of autophagy in Parkinson's disease: rotenone-based modeling
por: Xiong, Nian, et al.
Publicado: (2013)

The ventral striatum contributes to the activity of the motor cortex and motor outputs in monkeys
por: Suzuki, Michiaki, et al.
Publicado: (2022)

Adenosine A(2A) Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism
por: Fathalla, Ahmed M., et al.
Publicado: (2016)

Transient exposure to rotenone causes degeneration and progressive parkinsonian motor deficits, neuroinflammation, and synucleinopathy
por: Van Laar, Amber D., et al.
Publicado: (2023)

Sulforaphane protects against rotenone-induced neurotoxicity in vivo: Involvement of the mTOR, Nrf2, and autophagy pathways
por: Zhou, Qian, et al.
Publicado: (2016)

Ellagic acid protects dopamine neurons from rotenone‐induced neurotoxicity via activation of Nrf2 signalling
por: Wei, Yi‐zheng, et al.
Publicado: (2020)

Neuroprotective potential of ferulic acid in the rotenone model of Parkinson’s disease
por: Ojha, Shreesh, et al.
Publicado: (2015)

Commentary: Adenosine A(2A) Receptor Blockade Prevents Rotenone-Induced Motor Impairment in a Rat Model of Parkinsonism
por: de Souza, Marina F., et al.
Publicado: (2017)

Sericin alleviates motor dysfunction by modulating inflammation and TrkB/BDNF signaling pathway in the rotenone-induced Parkinson’s disease model
por: Salari, Zahra, et al.
Publicado: (2023)

Nr4a1-eGFP Is a Marker of Striosome-Matrix Architecture, Development and Activity in the Extended Striatum
por: Davis, Margaret I., et al.
Publicado: (2011)

Reduction of NrF2 as coadjuvant during the development of persistent periapical lesions
por: Guerrero-Bobadilla, Carlos, et al.
Publicado: (2023)

The Striatum and Subthalamic Nucleus as Independent and Collaborative Structures in Motor Control
por: Tewari, Alia, et al.
Publicado: (2016)

Edaravone Guards Dopamine Neurons in a Rotenone Model for Parkinson's Disease
por: Xiong, Nian, et al.
Publicado: (2011)

Stereotaxical Infusion of Rotenone: A Reliable Rodent Model for Parkinson's Disease
por: Xiong, Nian, et al.
Publicado: (2009)

Progression of Parkinson's Disease Pathology Is Reproduced by Intragastric Administration of Rotenone in Mice
por: Pan-Montojo, Francisco, et al.
Publicado: (2010)

Gastrodin inhibits neuroinflammation in rotenone-induced Parkinson's disease model rats★
por: Li, Chun, et al.
Publicado: (2012)

Evidence of Oropharyngeal Dysfunction in Feeding in the Rat Rotenone Model of Parkinson's Disease
por: Gould, François D. H., et al.
Publicado: (2018)

Non-Reproducibility of Oral Rotenone as a Model for Parkinson’s Disease in Mice
por: Niederberger, Ellen, et al.
Publicado: (2022)

Mitochondrial Dysfunction and Oxidative Stress Promote Apoptotic Cell Death in the Striatum via Cytochrome c/Caspase-3 Signaling Cascade Following Chronic Rotenone Intoxication in Rats
por: Lin, Tsu-Kung, et al.
Publicado: (2012)

Correction: Nr4a1-eGFP Is a Marker of Striosome-Matrix Architecture, Development and Activity in the Extended Striatum
por: Davis, Margaret I., et al.
Publicado: (2011)

Bee Venom Protects against Rotenone-Induced Cell Death in NSC34 Motor Neuron Cells
por: Jung, So Young, et al.
Publicado: (2015)

Neuroprotective Effect of Phloretin in Rotenone-Induced Mice Model of Parkinson’s Disease: Modulating mTOR-NRF2-p62 Mediated Autophagy-Oxidative Stress Crosstalk
por: Shirgadwar, Shubhendu M., et al.
Publicado: (2023)

Chronic Systemic Exposure to Low-Dose Rotenone Induced Central and Peripheral Neuropathology and Motor Deficits in Mice: Reproducible Animal Model of Parkinson’s Disease
por: Miyazaki, Ikuko, et al.
Publicado: (2020)

Distinct roles for motor cortical and thalamic inputs to striatum during motor skill learning and execution
por: Wolff, Steffen B. E., et al.
Publicado: (2022)

Excessive levels of nitric oxide in rat model of Parkinson’s disease induced by rotenone
por: XIONG, ZHONG-KUI, et al.
Publicado: (2015)

Treadmill exercise alleviates depressive symptoms in rotenone-induced Parkinson disease rats
por: Shin, Mal-Soon, et al.
Publicado: (2017)

Olfactory impairment is related to REM sleep deprivation in rotenone model of Parkinson's disease
por: Aurich, Mariana F., et al.
Publicado: (2017)

Involvement of Akt/mTOR in the Neurotoxicity of Rotenone-Induced Parkinson’s Disease Models
por: Zhang, Yu, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_ii9opp5aplinhs5oah2tuaa18l