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Estrogen receptor α/prolactin receptor bilateral crosstalk promotes bromocriptine resistance in prolactinomas

Prolactinomas are the most common type of functional pituitary adenoma. Although bromocriptine is the preferred first line treatment for prolactinoma, resistance frequently occurs, posing a prominent clinical challenge. Both the prolactin receptor (PRLR) and estrogen receptor α (ERα) serve critical...

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Detalles Bibliográficos
Autores principales: Xiao, Zhengzheng, Yang, Xiaoli, Zhang, Kun, Liu, Zebin, Shao, Zheng, Song, Chaojun, Wang, Xiaobin, Li, Zhengwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646122/
https://www.ncbi.nlm.nih.gov/pubmed/33173437
http://dx.doi.org/10.7150/ijms.51176