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FLRT2 functions as Tumor Suppressor gene inactivated by promoter methylation in Colorectal Cancer

Colorectal cancer (CRC) is a leading cause of cancer death worldwide. Epigenetic alterations, especially DNA methylation, contribute to the initiation and progression of CRC. To identify novel methylated tumor suppressors in CRC, MethylRAD-Seq screening was performed. As the result, FLRT2 was found...

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Detalles Bibliográficos
Autores principales: Guo, Xiaohong, Song, Chao, Fang, Lei, Li, Min, Yue, Longtao, Sun, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646184/
https://www.ncbi.nlm.nih.gov/pubmed/33193897
http://dx.doi.org/10.7150/jca.47558