Quality by Design Approach for Preparation of Zolmitriptan/Chitosan Nanostructured Lipid Carrier Particles – Formulation and Pharmacodynamic Assessment

PURPOSE: Zolmitriptan (ZT) is a selective serotonin agonist that is used for the treatment of migraine. It belongs to BCS class III with high solubility and low permeability. Besides, the drug is subjected to pre-systemic metabolism. Accordingly, new Zolmitriptan/chitosan nanostructured lipid carrie...

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Detalles Bibliográficos
Autores principales: Awadeen, Randa Hanie, Boughdady, Mariza Fouad, Meshali, Mahasen Mohamed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646415/
https://www.ncbi.nlm.nih.gov/pubmed/33173292
http://dx.doi.org/10.2147/IJN.S274352

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646415/
https://www.ncbi.nlm.nih.gov/pubmed/33173292
http://dx.doi.org/10.2147/IJN.S274352

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