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Let-7c-5p Inhibits Cell Proliferation and Migration and Promotes Apoptosis via the CTHRC1/AKT/ERK Pathway in Esophageal Squamous Cell Carcinoma

PURPOSE: Let-7c-5p has been identified as a tumor suppressor in various malignancies; however, its function and mechanism in esophageal squamous cell carcinoma (ESCC) remain unclear. Here, we explored the role and potential molecular mechanism of let-7c-5p in ESCC. MATERIALS AND METHODS: mRNA and pr...

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Detalles Bibliográficos
Autores principales: Zheng, Yaxin, Luo, Mao, Lü, Muhan, Zhou, Tiejun, Liu, Fang, Guo, Xiaoni, Zhang, Jian, Kang, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646436/
https://www.ncbi.nlm.nih.gov/pubmed/33173311
http://dx.doi.org/10.2147/OTT.S274092