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Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo

Many flaviviruses including the Dengue virus (DENV), Zika virus (ZIKV), West Nile virus, Yellow Fever virus, and Japanese encephalitis virus are significant human pathogens, unfortunately without any specific therapy. Here, we demonstrate that methylene blue, an FDA-approved drug, is a broad-spectru...

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Detalles Bibliográficos
Autores principales: Li, Zhong, Lang, Yuekun, Sakamuru, Srilatha, Samrat, Subodh, Trudeau, Nicole, Kuo, Lili, Rugenstein, Natasha, Tharappel, Anil, D'Brant, Lianna, Koetzner, Cheri A., Hu, Saiyang, Zhang, Jing, Huang, Ruili, Kramer, Laura D., Butler, David, Xia, Menghang, Li, Hongmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646565/
https://www.ncbi.nlm.nih.gov/pubmed/33078696
http://dx.doi.org/10.1080/22221751.2020.1838954