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Butyrate enhances the efficacy of radiotherapy via FOXO3A in colorectal cancer patient-derived organoids

Enhancing the radioresponsiveness of colorectal cancer (CRC) is essential for local control and prognosis. However, consequent damage to surrounding healthy cells can lead to treatment failure. We hypothesized that short-chain fatty acids (SCFAs) could act as radiosensitizers for cancer cells, allow...

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Detalles Bibliográficos
Autores principales: Park, Misun, Kwon, Junhye, Shin, Hye-Jin, Moon, Sun Mi, Kim, Sang Bum, Shin, Ui Sup, Han, Young-Hoon, Kim, Younjoo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646587/
https://www.ncbi.nlm.nih.gov/pubmed/33173975
http://dx.doi.org/10.3892/ijo.2020.5132