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Efficacy of Tocilizumab in Patients Hospitalized with Covid-19

BACKGROUND: The efficacy of interleukin-6 receptor blockade in hospitalized patients with coronavirus disease 2019 (Covid-19) who are not receiving mechanical ventilation is unclear. METHODS: We performed a randomized, double-blind, placebo-controlled trial involving patients with confirmed severe a...

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Detalles Bibliográficos
Autores principales: Stone, John H., Frigault, Matthew J., Serling-Boyd, Naomi J., Fernandes, Ana D., Harvey, Liam, Foulkes, Andrea S., Horick, Nora K., Healy, Brian C., Shah, Ruta, Bensaci, Ana Maria, Woolley, Ann E., Nikiforow, Sarah, Lin, Nina, Sagar, Manish, Schrager, Harry, Huckins, David S., Axelrod, Matthew, Pincus, Michael D., Fleisher, Jorge, Sacks, Chana A., Dougan, Michael, North, Crystal M., Halvorsen, Yuan-Di, Thurber, Tara K., Dagher, Zeina, Scherer, Allison, Wallwork, Rachel S., Kim, Arthur Y., Schoenfeld, Sara, Sen, Pritha, Neilan, Tomas G., Perugino, Cory A., Unizony, Sebastian H., Collier, Deborah S., Matza, Mark A., Yinh, Janeth M., Bowman, Kathryn A., Meyerowitz, Eric, Zafar, Amna, Drobni, Zsofia D., Bolster, Marcy B., Kohler, Minna, D’Silva, Kristin M., Dau, Jonathan, Lockwood, Megan M., Cubbison, Caroline, Weber, Brittany N., Mansour, Michael K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Massachusetts Medical Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646626/
https://www.ncbi.nlm.nih.gov/pubmed/33085857
http://dx.doi.org/10.1056/NEJMoa2028836