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STAT3 isoforms differentially affect ACE2 expression: A potential target for COVID‐19 therapy

The SARS‐coronavirus 2 is the aetiologic agent COVID‐19. ACE2 has been identified as a cell entry receptor for the virus. Therefore, trying to understand how the gene is controlled has become a major goal. We silenced the expression of STAT3α and STAT3β, and found that while silencing STAT3α causes...

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Detalles Bibliográficos
Autores principales: Shamir, Inbal, Abutbul‐Amitai, Mor, Abbas‐Egbariya, Haya, Pasmanik‐Chor, Metsada, Paret, Gideon, Nevo‐Caspi, Yael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646643/
https://www.ncbi.nlm.nih.gov/pubmed/32949179
http://dx.doi.org/10.1111/jcmm.15838