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Targeting an engineered cytokine with interleukin-2 and interleukin-15 activity to the neovasculature of solid tumors
There is a growing interest in the antibody-based delivery of cytokines to the tumor environment as a means to boost the anti-cancer activity of tumor-resident T cells and NK cells. Here, we describe the expression and characterization of fusion proteins, featuring the L19 antibody (specific to the...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Impact Journals LLC
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646832/ https://www.ncbi.nlm.nih.gov/pubmed/33216834 http://dx.doi.org/10.18632/oncotarget.27772 |