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Knockdown of AMPKα2 impairs epithelial-mesenchymal transition in rat renal tubular epithelial cells by downregulating ETS1 and RPS6KA1

Epithelial-mesenchymal transition (EMT) serves an important regulatory role in obstructive nephropathy and renal fibrosis. As an intracellular energy sensor, AMP-activated protein kinase (AMPK) is essential in the process of EMT. The aim of the present study was to elucidate changes in the expressio...

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Detalles Bibliográficos
Autores principales: Yin, Xiaoming, Ma, Fujiang, Fan, Xu, Zhao, Qi, Liu, Xin, Yang, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646838/
https://www.ncbi.nlm.nih.gov/pubmed/33173986
http://dx.doi.org/10.3892/mmr.2020.11556