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Narasin inhibits tumor metastasis and growth of ERα-positive breast cancer cells by inactivation of the TGF-β/SMAD3 and IL-6/STAT3 signaling pathways

Treatment of human estrogen receptor (ER)-positive breast cancer (ER(+) BC) using conventional chemotherapy remains a challenge and is often ineffective as a result of tumor metastasis. The present study aimed to investigate the ability of narasin, an ionophore antibiotic, to potentially inhibit tum...

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Detalles Bibliográficos
Autores principales: Chen, Jing, Huang, Xieping, Li, Na, Liu, Boxia, Ma, Zhanbing, Ling, Jun, Yang, Wenjun, Li, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646975/
https://www.ncbi.nlm.nih.gov/pubmed/33174044
http://dx.doi.org/10.3892/mmr.2020.11624