MicroRNA-494 suppresses hypoxia/reoxygenation-induced cardiomyocyte apoptosis and autophagy via the PI3K/AKT/mTOR signaling pathway by targeting SIRT1

Acute myocardial infarction can be caused by ischemia/reperfusion (I/R) injury; however, the mechanism underlying I/R is not completely understood. The present study investigated the functions and mechanisms underlying microRNA (miR)-494 in I/R-induced cardiomyocyte apoptosis and autophagy. Hypoxia/...

Descripción completa

Detalles Bibliográficos
Autores principales: Ning, Shuwei, Li, Zhiying, Ji, Zhenyu, Fan, Dandan, Wang, Keke, Wang, Qian, Hua, Lei, Zhang, Junyue, Meng, Xiangguang, Yuan, Yiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646990/
https://www.ncbi.nlm.nih.gov/pubmed/33174056
http://dx.doi.org/10.3892/mmr.2020.11636

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646990/
https://www.ncbi.nlm.nih.gov/pubmed/33174056
http://dx.doi.org/10.3892/mmr.2020.11636

Ejemplares similares