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Knockdown of exosome-mediated lnc-PVT1 alleviates lipopolysaccharide-induced osteoarthritis progression by mediating the HMGB1/TLR4/NF-κB pathway via miR-93-5p

Osteoarthritis is a chronic degenerative joint disease. Long non-coding RNA plasmacytoma variant translocation 1 (PVT1) is involved in the progression of osteoarthritis and exosomes serve a central role in intercellular communication. However, whether PVT1 can be mediated by exosomes in osteoarthrit...

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Detalles Bibliográficos
Autores principales: Meng, Yong, Qiu, Siqiang, Sun, Long, Zuo, Jinliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7646997/
https://www.ncbi.nlm.nih.gov/pubmed/33174011
http://dx.doi.org/10.3892/mmr.2020.11594