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Declining antibody levels to Trypanosoma cruzi correlate with polymerase chain reaction positivity and electrocardiographic changes in a retrospective cohort of untreated Brazilian blood donors

BACKGROUND: Although infection with Trypanosoma cruzi is thought to be lifelong, less than half of those infected develop cardiomyopathy, suggesting greater parasite control or even clearance. Antibody levels appear to correlate with T. cruzi (antigen) load. We test the association between a downwar...

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Detalles Bibliográficos
Autores principales: Buss, Lewis F., Campos de Oliveira- da Silva, Léa, Moreira, Carlos H. V., Manuli, Erika R., Sales, Flavia C., Morales, Ingra, Di Germanio, Clara, de Almeida-Neto, Cesar, Bakkour, Sonia, Constable, Paul, Pinto-Filho, Marcelo M., Ribeiro, Antonio L., Busch, Michael, Sabino, Ester C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647114/
https://www.ncbi.nlm.nih.gov/pubmed/33108390
http://dx.doi.org/10.1371/journal.pntd.0008787