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p53 promotes ZDHHC1-mediated IFITM3 palmitoylation to inhibit Japanese encephalitis virus replication

The tumor suppressor p53 as an innate antiviral regulator contributes to restricting Japanese encephalitis virus (JEV) replication, but the mechanism is still unclear. The interferon-induced transmembrane protein 3 (IFITM3) is an intrinsic barrier to a range of virus infection, whether IFITM3 is res...

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Detalles Bibliográficos
Autores principales: Wang, Xin, Wu, Zhuanchang, Li, Yuming, Yang, Yifan, Xiao, Changguang, Liu, Xiqian, Xiang, Xiao, Wei, Jianchao, Shao, Donghua, Liu, Ke, Deng, Xufang, Wu, Jiaqiang, Qiu, Yafeng, Li, Beibei, Ma, Zhiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647115/
https://www.ncbi.nlm.nih.gov/pubmed/33108395
http://dx.doi.org/10.1371/journal.ppat.1009035