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Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

Post-translational modifications such as ubiquitination are important for orchestrating the cellular transformations that occur as the Leishmania parasite differentiates between its main morphological forms, the promastigote and amastigote. 2 E1 ubiquitin-activating (E1), 13 E2 ubiquitin-conjugating...

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Detalles Bibliográficos
Autores principales: Burge, Rebecca J., Damianou, Andreas, Wilkinson, Anthony J., Rodenko, Boris, Mottram, Jeremy C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647121/
https://www.ncbi.nlm.nih.gov/pubmed/33108402
http://dx.doi.org/10.1371/journal.ppat.1008784