Cargando…

Leishmania differentiation requires ubiquitin conjugation mediated by a UBC2-UEV1 E2 complex

Post-translational modifications such as ubiquitination are important for orchestrating the cellular transformations that occur as the Leishmania parasite differentiates between its main morphological forms, the promastigote and amastigote. 2 E1 ubiquitin-activating (E1), 13 E2 ubiquitin-conjugating...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burge, Rebecca J., Damianou, Andreas, Wilkinson, Anthony J., Rodenko, Boris, Mottram, Jeremy C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647121/ https://www.ncbi.nlm.nih.gov/pubmed/33108402 http://dx.doi.org/10.1371/journal.ppat.1008784

Ejemplares similares

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A
por: Andersen, Parker L., et al.
Publicado: (2005)

Functional Characterization of Potato UBC13-UEV1s Genes Required for Ubiquitin Lys63 Chain to Polyubiquitination
por: Liu, Weigang, et al.
Publicado: (2023)

Essential roles for deubiquitination in Leishmania life cycle progression
por: Damianou, Andreas, et al.
Publicado: (2020)

Arabidopsis Ubiquitin-Conjugating Enzymes UBC7, UBC13, and UBC14 Are Required in Plant Responses to Multiple Stress Conditions
por: Feng, Hui, et al.
Publicado: (2020)

Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation
por: Wu, Zhaojia, et al.
Publicado: (2014)

Erratum to: Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation
por: Wu, Zhaojia, et al.
Publicado: (2017)

UEV-1 Is an Ubiquitin-Conjugating Enzyme Variant That Regulates Glutamate Receptor Trafficking in C. elegans Neurons
por: Kramer, Lawrence B., et al.
Publicado: (2010)

Arabidopsis Ubiquitin-Conjugating Enzymes UBC4, UBC5, and UBC6 Have Major Functions in Sugar Metabolism and Leaf Senescence
por: Wang, Sheng, et al.
Publicado: (2022)

Three Brachypodium distachyon Uev1s Promote Ubc13-Mediated Lys63-Linked Polyubiquitination and Confer Different Functions
por: Guo, Huiping, et al.
Publicado: (2016)

Tetrahydrobiopterin modulates ubiquitin conjugation to UBC13/UBE2N and proteasome activity by S-nitrosation
por: Bailey, Jade, et al.
Publicado: (2018)

Arabidopsis ubiquitin-conjugating enzyme UBC22 is required for female gametophyte development and likely involved in Lys11-linked ubiquitination
por: Wang, Sheng, et al.
Publicado: (2016)

UBC13 is an RNF213‐associated E2 ubiquitin‐conjugating enzyme, and Lysine 63‐linked ubiquitination by the RNF213‐UBC13 axis is responsible for angiogenic activity
por: Habu, Toshiyuki, et al.
Publicado: (2021)

Ubiquitin control of S phase: a new role for the ubiquitin conjugating enzyme, UbcH7
por: Whitcomb, Elizabeth A, et al.
Publicado: (2009)

The Ubiquitin Conjugating Enzyme UbcD1 is Required for Notch Signaling Activation During Drosophila Wing Development
por: Zhang, Fengchao, et al.
Publicado: (2021)

A novel requirement for ubiquitin-conjugating enzyme UBC-13 in retrograde recycling of MIG-14/Wntless and Wnt signaling
por: Zhang, Junbing, et al.
Publicado: (2018)

Uev1A-Ubc13 promotes colorectal cancer metastasis through regulating CXCL1 expression via NF-кB activation
por: Wu, Zhaojia, et al.
Publicado: (2018)

Structural analysis of recombinant human ubiquitin-conjugating enzyme UbcH5c
por: Wu, Fangshu, et al.
Publicado: (2017)

Ubiquitin-Conjugating Enzymes Ubc1 and Ubc4 Mediate the Turnover of Hap4, a Master Regulator of Mitochondrial Biogenesis in Saccharomyces cerevisiae
por: Capps, Denise, et al.
Publicado: (2022)

Overexpression of the E2 ubiquitin–conjugating enzyme UbcH10 causes chromosome missegregation and tumor formation
por: van Ree, Janine H., et al.
Publicado: (2010)

Ubiquitin-Conjugating Enzyme OsUBC11 Affects the Development of Roots via Auxin Pathway
por: Han, Yunfei, et al.
Publicado: (2023)

Rigorous characterization of urinary extracellular vesicles (uEVs) in the low centrifugation pellet - a neglected source for uEVs
por: Musante, Luca, et al.
Publicado: (2020)

The Ubiquitin-Conjugating Enzyme, UbcM2, Is Restricted to Monoubiquitylation by a Two-Fold Mechanism That Involves Backside Residues of E2 and Lys48 of Ubiquitin
por: Nguyen, Linda, et al.
Publicado: (2014)

Rice ubiquitin‐conjugating enzyme OsUBC26 is essential for immunity to the blast fungus Magnaporthe oryzae
por: Liu, Xin, et al.
Publicado: (2021)

The ubiquitin-conjugating enzyme, Ubc1, indirectly regulates SNF1 kinase activity via Forkhead-dependent transcription
por: Jiao, Rubin, et al.
Publicado: (2016)

Uev1A facilitates osteosarcoma differentiation by promoting Smurf1-mediated Smad1 ubiquitination and degradation
por: Zhang, Weiwei, et al.
Publicado: (2017)

The UBA domain of conjugating enzyme Ubc1/Ube2K facilitates assembly of K48/K63‐branched ubiquitin chains
por: Pluska, Lukas, et al.
Publicado: (2021)

Ubc13: the Lys63 ubiquitin chain building machine
por: Hodge, Curtis D., et al.
Publicado: (2016)

Overexpression of VrUBC1, a Mung Bean E2 Ubiquitin-Conjugating Enzyme, Enhances Osmotic Stress Tolerance in Arabidopsis
por: Chung, Eunsook, et al.
Publicado: (2013)

Expression profiling of the ubiquitin conjugating enzyme UbcM2 in murine brain reveals modest age-dependent decreases in specific neurons
por: Larabee, Chelsea M., et al.
Publicado: (2015)

HECT domain interaction with ubiquitin binding sites on Tsg101-UEV controls HIV-1 egress, maturation, and infectivity
por: Nyenhuis, David A., et al.
Publicado: (2023)

Targeting E2 ubiquitin-conjugating enzyme UbcH5c by small molecule inhibitor suppresses pancreatic cancer growth and metastasis
por: Qi, Simin, et al.
Publicado: (2022)

Characterization of four rice UEV1 genes required for Lys63-linked polyubiquitination and distinct functions
por: Wang, Qian, et al.
Publicado: (2017)

Molecular Simulation Elaborating the Mechanism of 1β-Hydroxy Alantolactone Inhibiting Ubiquitin-Conjugating Enzyme UbcH5s
por: Xu, Youdong, et al.
Publicado: (2020)

A molecular basis for phosphorylation-dependent SUMO conjugation by the E2 Ubc9
por: Mohideen, Firaz, et al.
Publicado: (2009)

Loss of ubiquitin-conjugating enzyme E2 (Ubc9) in macrophages exacerbates multiple low-dose streptozotocin-induced diabetes by attenuating M2 macrophage polarization
por: Wang, Faxi, et al.
Publicado: (2019)

The metabolite-controlled ubiquitin conjugase Ubc8 promotes mitochondrial protein import
por: Rödl, Saskia, et al.
Publicado: (2022)

Structural insights into non-covalent ubiquitin activation of the cIAP1-UbcH5B∼ubiquitin complex
por: Patel, Amrita, et al.
Publicado: (2019)

Elevating the level of Cdc34/Ubc3 ubiquitin-conjugating enzyme in mitosis inhibits association of CENP-E with kinetochores and blocks the metaphase alignment of chromosomes
por: Topper, Leana M., et al.
Publicado: (2001)

Polymorphism of UBC9 Gene Encoding the SUMO-E2-Conjugating Enzyme and Breast Cancer Risk
por: Wozniak, Katarzyna, et al.
Publicado: (2013)

Proteasome Inhibition Promotes Parkin-Ubc13 Interaction and Lysine 63-Linked Ubiquitination
por: Lim, Grace G. Y., et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_j20fjeg2qs831juaagmslhqhqp