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Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) brutally perils physical and mental health worldwide. Unavailability of effective anti-viral drug rendering global threat of COVID-19 caused by SARS-CoV-2. In this scenario, viral protease enzymes are crucial targets for drug discovery. Th...

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Detalles Bibliográficos
Autores principales: Amin, Sk. Abdul, Banerjee, Suvankar, Ghosh, Kalyan, Gayen, Shovanlal, Jha, Tarun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647411/
https://www.ncbi.nlm.nih.gov/pubmed/33191083
http://dx.doi.org/10.1016/j.bmc.2020.115860