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Combined effects of obesity and di-(2-ethylhexyl) phthalate on testosterone levels and kisspeptin/GPR54 expression in hypothalamus and testes of male mice

BACKGROUND: This study evaluated whether obese male mice exposed to di-(2-ethylhexyl) phthalate (DEHP) showed synergistic effects on testosterone levels and the potential underlying mechanism. METHODS: Forty-eight male mice were assigned to six groups for 12-week treatments as follows: normal, DEHP1...

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Detalles Bibliográficos
Autores principales: Zhai, Ling-Ling, Zhao, Jian, Bai, Ying-Long, Wei, Wei, Sun, Qi, Jia, Li-Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7647433/
https://www.ncbi.nlm.nih.gov/pubmed/32732529
http://dx.doi.org/10.1097/JCMA.0000000000000402