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RBPJ contributes to the malignancy of glioblastoma and induction of proneural‐mesenchymal transition via IL‐6‐STAT3 pathway

Notch signaling plays a pivotal role in many cancers, including glioblastoma (GBM). Recombination signal binding protein for immunoglobulin kappa J region (RBPJ) is a key transcription factor of the Notch signaling pathway. Here, we interrogated the function of RBPJ in GBM. Firstly, RBPJ expression...

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Detalles Bibliográficos
Autores principales: Zhang, Guangtao, Tanaka, Shingo, Jiapaer, Shabierjiang, Sabit, Hemragul, Tamai, Sho, Kinoshita, Masashi, Nakada, Mitsutoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648018/
https://www.ncbi.nlm.nih.gov/pubmed/32885530
http://dx.doi.org/10.1111/cas.14642