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Hypoxia‐inducible hexokinase‐2 enhances anti‐apoptotic function via activating autophagy in multiple myeloma

Multiple myeloma (MM) is an incurable hematopoietic neoplasm derived from plasma cells, and existing in the bone marrow. Recent developments in the field of myeloma onco‐biology have enabled the use of proteasome inhibitors (PIs) as key drugs for MM. PIs can increase cell sensitivity to endoplasmic...

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Detalles Bibliográficos
Autores principales: Ikeda, Sho, Abe, Fumito, Matsuda, Yuka, Kitadate, Akihiro, Takahashi, Naoto, Tagawa, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648043/
https://www.ncbi.nlm.nih.gov/pubmed/32790954
http://dx.doi.org/10.1111/cas.14614