Cargando…

Hypoxia‐inducible hexokinase‐2 enhances anti‐apoptotic function via activating autophagy in multiple myeloma

Multiple myeloma (MM) is an incurable hematopoietic neoplasm derived from plasma cells, and existing in the bone marrow. Recent developments in the field of myeloma onco‐biology have enabled the use of proteasome inhibitors (PIs) as key drugs for MM. PIs can increase cell sensitivity to endoplasmic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ikeda, Sho, Abe, Fumito, Matsuda, Yuka, Kitadate, Akihiro, Takahashi, Naoto, Tagawa, Hiroyuki
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648043/ https://www.ncbi.nlm.nih.gov/pubmed/32790954 http://dx.doi.org/10.1111/cas.14614

Ejemplares similares

Hypoxia‐induced oxidative stress promotes therapy resistance via upregulation of heme oxygenase‐1 in multiple myeloma
por: Abe, Ko, et al.
Publicado: (2023)

Downregulation of miR‐26 promotes invasion and metastasis via targeting interleukin‐22 in cutaneous T‐cell lymphoma
por: Matsuda, Yuka, et al.
Publicado: (2022)

Hypoxia‐inducible microRNA‐210 regulates the DIMT1‐IRF4 oncogenic axis in multiple myeloma
por: Ikeda, Sho, et al.
Publicado: (2017)

Histone deacetylase inhibitors downregulate CCR4 expression and decrease mogamulizumab efficacy in CCR4-positive mature T-cell lymphomas
por: Kitadate, Akihiro, et al.
Publicado: (2018)

Disruption of CCL20-CCR6 interaction inhibits metastasis of advanced cutaneous T-cell lymphoma
por: Ikeda, Sho, et al.
Publicado: (2016)

Impact of hypoxia on the pathogenesis and therapy resistance in multiple myeloma
por: Ikeda, Sho, et al.
Publicado: (2021)

Histone deacetylase inhibitors inhibit metastasis by restoring a tumor suppressive microRNA-150 in advanced cutaneous T-cell lymphoma
por: Abe, Fumito, et al.
Publicado: (2016)

Multiple myeloma with t(11;14)‐associated immature phenotype has lower CD38 expression and higher BCL2 dependence
por: Kitadate, Akihiro, et al.
Publicado: (2021)

P1272: GP130/STAT3 AXIS IS A POTENTIAL THERAPEUTIC TARGET FOR HISTONE DEACETYLASE INHIBITOR-RESISTANT CUTANEOUS T-CELL LYMPHOMA
por: Takahashi, Y., et al.
Publicado: (2022)

N-terminal pro-brain natriuretic peptide reflects both left ventricular diastolic dysfunction and myeloma-related renal insufficiency and robustly predicts mortality in patients with symptomatic multiple myeloma
por: Abe, Yoshiaki, et al.
Publicado: (2019)

Association between serum erythropoietin levels and renal reversibility in patients with renal impairment from multiple myeloma
por: Kobayashi, Hiroki, et al.
Publicado: (2020)

Deregulation of Hexokinase II Is Associated with Glycolysis, Autophagy, and the Epithelial-Mesenchymal Transition in Tongue Squamous Cell Carcinoma under Hypoxia
por: Chen, Guanhui, et al.
Publicado: (2018)

Improved survival outcomes and relative youthfulness of multiple myeloma patients with t(4;14) receiving novel agents are associated with poorer performance of the revised international staging system in a real aging society
por: Abe, Yoshiaki, et al.
Publicado: (2019)

Hexokinase 2 is a molecular bridge linking telomerase and autophagy
por: Roh, Jae-il, et al.
Publicado: (2018)

c‐FOS is an integral component of the IKZF1 transactivator complex and mediates lenalidomide resistance in multiple myeloma
por: Osada, Naoki, et al.
Publicado: (2023)

Analysis of the anti-proliferative and the pro-apoptotic efficacy of Syk inhibition in multiple myeloma
por: Koerber, Ruth-Miriam, et al.
Publicado: (2015)

Cyclin D1 targets hexokinase 2 to control aerobic glycolysis in myeloma cells
por: Caillot, M., et al.
Publicado: (2020)

Hexokinase 2 as oncotarget
por: Patra, Krushna C., et al.
Publicado: (2013)

Bortezomib Reduces the Tumorigenicity of Multiple Myeloma via Downregulation of Upregulated Targets in Clonogenic Side Population Cells
por: Nara, Miho, et al.
Publicado: (2013)

Apoptotic Machinery Diversity in Multiple Myeloma Molecular Subtypes
por: Gomez-Bougie, Patricia, et al.
Publicado: (2013)

A precision therapeutic strategy for hexokinase 1-null, hexokinase 2-positive cancers
por: Xu, Shili, et al.
Publicado: (2018)

Moonlighting Proteins: The Case of the Hexokinases
por: Rodríguez-Saavedra, Carolina, et al.
Publicado: (2021)

Hexokinases in cancer and other pathologies
por: Guo, Dong, et al.
Publicado: (2023)

The Emi2 Protein of Saccharomyces cerevisiae is a Hexokinase Expressed under Glucose Limitation
por: Umekawa, Midori, et al.
Publicado: (2020)

Molecular Cloning and Functional Characterization of a Hexokinase from the Oriental River Prawn Macrobrachium nipponense in Response to Hypoxia
por: Sun, Shengming, et al.
Publicado: (2017)

Hexokinase 2 confers radio-resistance in hepatocellular carcinoma by promoting autophagy-dependent degradation of AIMP2
por: Zheng, Yilin, et al.
Publicado: (2023)

Acute Myeloid Leukemia Harboring the t(16;21)(p11;q22) Translocation Treated With Venetoclax Plus Azacitidine After Cord Blood Transplantation
por: Teshima, Kazuaki, et al.
Publicado: (2023)

A Novel Mutant from Apoptosis‐resistant Colon Cancer HT‐29 Cells Showing Hyper‐apoptotic Response to Hypoxia, Low Glucose and Cisplatin
por: Suzuki, Hiroyuki, et al.
Publicado: (1998)

Multiple Myeloma–Associated Ig Light Chain Crystalline Cast Nephropathy
por: Matsumura, Hirotoshi, et al.
Publicado: (2020)

ISOLATION OF PURE HEXOKINASE FROM YEAST
por: Berger, Louis, et al.
Publicado: (1946)

ISOLATION OF HEXOKINASE FROM BAKER'S YEAST
por: Berger, Louis, et al.
Publicado: (1946)

Regulation and Cytoprotective Role of Hexokinase III
por: Wyatt, Eugene, et al.
Publicado: (2010)

Functional domains of yeast hexokinase 2
por: Peláez, Rafael, et al.
Publicado: (2010)

Hexokinase 2 Is a Pivot for Lovastatin-induced Glycolysis-to-Autophagy Reprogramming in Triple-Negative Breast Cancer Cells
por: Xue, Lian, et al.
Publicado: (2022)

Hexokinase-II Inhibition Synergistically Augments the Anti-tumor Efficacy of Sorafenib in Hepatocellular Carcinoma
por: Yoo, Jeong-Ju, et al.
Publicado: (2019)

Virtual Screening for Potential Inhibitors of Human Hexokinase II for the Development of Anti-Dengue Therapeutics
por: Tanbin, Suriyea, et al.
Publicado: (2020)

Bortezomib Treatment Modulates Autophagy in Multiple Myeloma
por: Di Lernia, Giuseppe, et al.
Publicado: (2020)

Regulation of Fungal Morphogenesis and Pathogenicity of Aspergillus flavus by Hexokinase AfHxk1 through Its Domain Hexokinase_2
por: Huang, Zongting, et al.
Publicado: (2023)

Role of vasorin, an anti‐apoptotic, anti‐TGF‐β and hypoxia‐induced glycoprotein in the trabecular meshwork cells and glaucoma
por: Choi, Jin A., et al.
Publicado: (2022)

Hexokinase 2 in Cancer: A Prima Donna Playing Multiple Characters
por: Ciscato, Francesco, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_g8pg1us1rp7nn9ets16b440gtt