The nuclear pore primes recombination-dependent DNA synthesis at arrested forks by promoting SUMO removal

Nuclear Pore complexes (NPCs) act as docking sites to anchor particular DNA lesions facilitating DNA repair by elusive mechanisms. Using replication fork barriers in fission yeast, we report that relocation of arrested forks to NPCs occurred after Rad51 loading and its enzymatic activity. The E3 SUM...

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Detalles Bibliográficos
Autores principales: Kramarz, Karol, Schirmeisen, Kamila, Boucherit, Virginie, Ait Saada, Anissia, Lovo, Claire, Palancade, Benoit, Freudenreich, Catherine, Lambert, Sarah A. E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648084/
https://www.ncbi.nlm.nih.gov/pubmed/33159083
http://dx.doi.org/10.1038/s41467-020-19516-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648084/
https://www.ncbi.nlm.nih.gov/pubmed/33159083
http://dx.doi.org/10.1038/s41467-020-19516-z

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