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Injury triggers fascia fibroblast collective cell migration to drive scar formation through N-cadherin

Scars are more severe when the subcutaneous fascia beneath the dermis is injured upon surgical or traumatic wounding. Here, we present a detailed analysis of fascia cell mobilisation by using deep tissue intravital live imaging of acute surgical wounds, fibroblast lineage-specific transgenic mice, a...

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Detalles Bibliográficos
Autores principales: Jiang, Dongsheng, Christ, Simon, Correa-Gallegos, Donovan, Ramesh, Pushkar, Kalgudde Gopal, Shruthi, Wannemacher, Juliane, Mayr, Christoph H., Lupperger, Valerio, Yu, Qing, Ye, Haifeng, Mück-Häusl, Martin, Rajendran, Vijayanand, Wan, Li, Liu, Juan, Mirastschijski, Ursula, Volz, Thomas, Marr, Carsten, Schiller, Herbert B., Rinkevich, Yuval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648088/
https://www.ncbi.nlm.nih.gov/pubmed/33159076
http://dx.doi.org/10.1038/s41467-020-19425-1