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Silencing KIF18B enhances radiosensitivity: identification of a promising therapeutic target in sarcoma

BACKGROUND: Sarcomas are rare heterogeneous tumours, derived from primitive mesenchymal stem cells, with more than 100 distinct subtypes. Radioresistance remains a major clinical challenge for sarcomas, demanding urgent for effective biomarkers of radiosensitivity. METHODS: The radiosensitive gene K...

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Detalles Bibliográficos
Autores principales: Liu, Wensi, Yu, Zhaojin, Tang, Haichao, Wang, Xiangyi, Zhang, Bing, Zhao, Jianhang, Liu, Xinli, Zhang, Jingdong, Wei, Minjie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648128/
https://www.ncbi.nlm.nih.gov/pubmed/33038765
http://dx.doi.org/10.1016/j.ebiom.2020.103056