Cargando…

Comparative analysis of differentially abundant proteins quantified by LC–MS/MS between flash frozen and laser microdissected OCT-embedded breast tumor samples

BACKGROUND: Proteomic studies are typically conducted using flash-frozen (FF) samples utilizing tandem mass spectrometry (MS). However, FF specimens are comprised of multiple cell types, making it difficult to ascertain the proteomic profiles of specific cells. Conversely, OCT-embedded (Optimal Cutt...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sturtz, Lori A., Wang, Guisong, Shah, Punit, Searfoss, Richard, Raj-Kumar, Praveen-Kumar, Hooke, Jeffrey A., Fantacone-Campbell, J. Leigh, Deyarmin, Brenda, Cutler, Mary Lou, Sarangarajan, Rangaprasad, Narain, Niven R., Hu, Hai, Kiebish, Michael A., Kovatich, Albert J., Shriver, Craig D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648272/ https://www.ncbi.nlm.nih.gov/pubmed/33292179 http://dx.doi.org/10.1186/s12014-020-09300-y

Ejemplares similares

Monoacylglycerol Analysis Using MS/MS(ALL) Quadruple Time of Flight Mass Spectrometry
por: Gao, Fei, et al.
Publicado: (2016)

Dynamic and temporal assessment of human dried blood spot MS/MS(ALL) shotgun lipidomics analysis
por: Gao, Fei, et al.
Publicado: (2017)

Current Status of Metabolomic Biomarker Discovery: Impact of Study Design and Demographic Characteristics
por: Tolstikov, Vladimir, et al.
Publicado: (2020)

Ethnic Prevalence of Angiotensin-Converting Enzyme Deletion (D) Polymorphism and COVID-19 Risk: Rationale for Use of Angiotensin-Converting Enzyme Inhibitors/Angiotensin Receptor Blockers
por: Sarangarajan, Rangaprasad, et al.
Publicado: (2020)

Genomic alterations of Tenascin C in highly aggressive prostate cancer: a meta-analysis
por: Mishra, Prachi, et al.
Publicado: (2019)

OMRT-13. Delivery of Ubidecarenone (BPM 31510) to mitochondria effectuates metabolic reprogramming and redox activated apoptosis in Glioblastoma
por: Sarangarajan, Rangaprasad, et al.
Publicado: (2021)

Impact of hemolysis on multi-OMIC pancreatic biomarker discovery to derisk biomarker development in precision medicine studies
por: Searfoss, Richard, et al.
Publicado: (2022)

Integrated Metabolomics Assessment of Human Dried Blood Spots and Urine Strips
por: Drolet, Jeremy, et al.
Publicado: (2017)

Ultrasensitive Quantification of Multiple Estrogens in Songbird Blood and Microdissected Brain by LC-MS/MS
por: Jalabert, Cecilia, et al.
Publicado: (2022)

Metabolomic effects of androgen deprivation therapy treatment for prostate cancer
por: Chi, Jen‐Tsan, et al.
Publicado: (2020)

Positive Association of Fibroadenomatoid Change with HER2-Negative Invasive Breast Cancer: A Co-Occurrence Study
por: Chen, Yaqin, et al.
Publicado: (2015)

PCA-PAM50 improves consistency between breast cancer intrinsic and clinical subtyping reclassifying a subset of luminal A tumors as luminal B
por: Raj-Kumar, Praveen-Kumar, et al.
Publicado: (2019)

Perturbation of the yeast mitochondrial lipidome and associated membrane proteins following heterologous expression of Artemia-ANT
por: Chen, Emily, et al.
Publicado: (2018)

High levels of ubidecarenone (oxidized CoQ(10)) delivered using a drug-lipid conjugate nanodispersion (BPM31510) differentially affect redox status and growth in malignant glioma versus non-tumor cells
por: Sun, Jiaxin, et al.
Publicado: (2020)

Identification of proteins in laser-microdissected small cell numbers by SELDI-TOF and Tandem MS
por: Kwapiszewska, Grazyna, et al.
Publicado: (2004)

Amplification of HER2 is a marker for global genomic instability
por: Ellsworth, Rachel E, et al.
Publicado: (2008)

Chronic stress and antidepressant treatment alter purine metabolism and beta oxidation within mouse brain and serum
por: Hamilton, Peter J., et al.
Publicado: (2020)

Extreme sediment fluxes in a dryland flash flood
por: Hooke, J. M.
Publicado: (2019)

Measurement of the Spatial Distribution of S1P in Small Quantities of Tissues: Development and Application of a Highly Sensitive LC-MS/MS Method Combined with Laser Microdissection
por: Wang, Jiao, et al.
Publicado: (2019)

Validation of MALDI-MS imaging data of selected membrane lipids in murine brain with and without laser postionization by quantitative nano-HPLC-MS using laser microdissection
por: Eiersbrock, Fabian B., et al.
Publicado: (2020)

Ubc1 turnover contributes to the spindle assembly checkpoint in Saccharomyces cerevisiae
por: Arsenault, Heather E, et al.
Publicado: (2021)

Using an FSDS-R Item to Screen for Sexually Related Distress: A MsFLASH Analysis
por: Carpenter, Janet S, et al.
Publicado: (2015)

Timing of retinal neuronal and axonal loss in MS: a longitudinal OCT study
por: Balk, Lisanne J., et al.
Publicado: (2016)

Laser capture microdissection coupled mass spectrometry (LCM-MS) for spatially resolved analysis of formalin-fixed and stained human lung tissues
por: Herrera, Jeremy A., et al.
Publicado: (2020)

Dysregulation of the calcium handling protein, CCDC47, is associated with diabetic cardiomyopathy
por: Thapa, Khampaseuth, et al.
Publicado: (2018)

Multi-omic serum biomarkers for prognosis of disease progression in prostate cancer
por: Kiebish, Michael A., et al.
Publicado: (2020)

Selection of optimal quantile protein biomarkers based on cell-level immunohistochemistry data
por: Yi, Misung, et al.
Publicado: (2023)

Hsp90β knockdown in DIO mice reverses insulin resistance and improves glucose tolerance
por: Jing, Enxuan, et al.
Publicado: (2018)

Molecular Heterogeneity in Primary Breast Carcinomas and Axillary Lymph Node Metastases Assessed by Genomic Fingerprinting Analysis
por: Ellsworth, Rachel E, et al.
Publicado: (2015)

Profiling the tumor microenvironment proteome in prostate cancer using laser capture microdissection coupled to LC⿿MS⿿A technical report
por: Staunton, L., et al.
Publicado: (2015)

Combination of laser microdissection, 2D-DIGE and MALDI-TOF MS to identify protein biomarkers to predict colorectal cancer spread
por: Kirana, Chandra, et al.
Publicado: (2019)

Modified microdissection electrocautery needle
por: Singh, Virendra, et al.
Publicado: (2014)

Pharmacological potential of Bidens pilosa L. and determination of bioactive compounds using UHPLC-QqQ(LIT)-MS/MS and GC/MS
por: Singh, Garima, et al.
Publicado: (2017)

Hypothesis-Agnostic Network-Based Analysis of Real-World Data Suggests Ondansetron is Associated with Lower COVID-19 Any Cause Mortality
por: Miller, Gregory M., et al.
Publicado: (2022)

Tissue-specific chemical profiling and quantitative analysis of bioactive components of Cinnamomum cassia by combining laser-microdissection with UPLC-Q/TOF–MS
por: Zhou, Wenwen, et al.
Publicado: (2018)

PAT-H-MS coupled with laser microdissection to study histone post-translational modifications in selected cell populations from pathology samples
por: Noberini, Roberta, et al.
Publicado: (2017)

Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
por: Zhang, Kai
Publicado: (2021)

Analysis of isoquinoline alkaloids from Mahonia leschenaultia and Mahonia napaulensis roots using UHPLC-Orbitrap-MS(n) and UHPLC-QqQ(LIT)-MS/MS
por: Singh, Awantika, et al.
Publicado: (2017)

Determination of Nine Fentanyl Drugs in Hair Samples by GC-MS/MS and LC-MS/MS
por: Wei, Qi, et al.
Publicado: (2022)

Determination of 355 Pesticides in Lemon and Lemon Juice by LC-MS/MS and GC-MS/MS
por: Aslantas, Sule, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_h5lc0noj12ran572t1g3tktggf