Superparamagnetic iron oxide nanoparticles conjugated with Aβ oligomer-specific scFv antibody and class A scavenger receptor activator show therapeutic potentials for Alzheimer’s Disease

BACKGROUND: Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. No disease-modifying strategy to prevent or delay AD progression currently exists. Aβ oligomers (AβOs), rather than monomers or fibrils, are considered as the primary neurotoxic species. Therapeutic approaches that dir...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Xiao-ge, Zhang, Lun, Lu, Shuai, Liu, Dong-qun, Huang, Ya-ru, Zhu, Jie, Zhou, Wei-wei, Yu, Xiao-lin, Liu, Rui-tian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648289/
https://www.ncbi.nlm.nih.gov/pubmed/33160377
http://dx.doi.org/10.1186/s12951-020-00723-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7648289/
https://www.ncbi.nlm.nih.gov/pubmed/33160377
http://dx.doi.org/10.1186/s12951-020-00723-1

Ejemplares similares